This concise and accessible resource offers new college students, especially those in science degree programs, guidance on engaging successfully with the classroom experience and skillfully tackling technical or scientific questions. The author provides insights on identifying, from the outset, individual markers for what success in college will look like for students, how to think about the engagement with professors as a partnership, and how to function effectively in that partnership toward achieving their pre-defined goals or markers of success. It is an ideal companion for science degree prospects and first-generation students seeking insight into the college experience.