In this medical thriller, three female doctors struggle to survive in a San Francisco hospital's "boy's club," as they encounter the challenges of the medical profession, a murder charge, and a deadly wager. The only three females in a group of new residents, the women quickly become roommates and friends, face long hours, a frenetic work pace, and unwanted advances from male colleagues. One becomes involved in unsavory underworld activities, another employs questionable medical skills that are overlooked by the male administrators who value her other services, and another tries to forget a lost love. Racing from life-and-death decisions to the tension-packed fireworks of a murder trial, Nothing Lasts Forever lays bare the ambitions and fears of healers and killers, lovers and betrayers.