The yard block of a container terminal is the central point of synchronisation for asynchronous container flows between deep-sea vessels and transport to the hinterland. The structure of the block stipulates that containers are stacked on top of each other with only the topmost container directly accessible by a yard crane. This book describes a holistic and integrative approach to container handling in yard blocks to optimise productivity by minimising re-handling operations. The results provide insights for academic scholars as well as for experts from practical terminal planning and operations. The approach presented is two-fold: first, a theoretical foundation of the interdependencies in decision-making is established using mathematical programming. Secondly, operations involving uncertain container arrival information are examined on the basis of a simulation with a rigorous experimental design and statistical evaluation. In this context, the book develops container-handling strategies and analyses the impact of a system for vehicle arrival management – the "Terminal Appointment System". The findings presented in this book are the result of a close cooperation with experts at the port of Hamburg and build on previous research.