This student-oriented manual describes how to use R in college science and mathematics courses. The manual features fully developed exercises based around the main precalculus analysis skills needed in the standard college general education courses in science and math. The exercises illustrate a wide variety of applications and subjects. The author presents applications drawn from all sciences and social sciences and includes the most often used features of R on a reference card in the back of the book. In addition, each chapter provides a set of computational challenges: exercises in R calculations that are designed to be performed alone or in groups.