This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:

· Evolution and detection of endogenous ADP-ribosylation

· ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs)

· ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs)

The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.