Daniel Blythe is a broken, twenty-nine-year-old man, obsessed and terrified with the reductionist philosophy of life, yet equally afraid of infinity pervading the reality that he knows. One night as he is walking alone through a small town in Arkansas, pining for the woman he loves, he is caught up in a cosmic journey with a mysterious, malevolent companion that threatens to undo everything he knows about life and his standing in creation.