This book provides readers a good overview of some of most recent advances in the field of hybrid pixelated detectors for X-ray imaging. Coverage includes both technology and applications, with an in-depth review of the research topics conducted at leading research institutions in the world. The conversion of the X-ray signal into an analogue/digital value is discussed, as well as a review of CMOS chips used for X-ray image sensors. Applications of hybrid pixel detectors are discussed, such as medical imaging, high energy physics, space, non-destructive testing and security.