This guidance note outlines how sector agencies in South Asia can develop gender equality and social inclusion (GESI) strategies, highlights their key elements, and shows how to effectively integrate them into projects and policies. Explaining how GESI strategies can help sector agencies tackle the barriers women and vulnerable groups face, it offers tips on how to adopt participatory processes to help develop and implement inclusive frameworks. It explains why sector agencies need to adapt strategies to their local norms and practices, allocate budgets, and adopt institutional policies to ensure GESI is effectively mainstreamed into organizations.