The story of Agatha and Devin is a sweeping saga spanning more than seventy years that begins with the tale of a misguided youth, Scott Robertson, who goes through his life living helter-skelter in ways that govern inevitable consequences. A strikingly handsome but undisciplined black male, Scott influences his unwitting juvenile counterpart, Monica Chisholm, to follow him into certain disaster. As a petty criminal, Scott, now father to seven impressionable children in the heart of the Harlem ghetto, is unchecked until he graduates into a hard-time felon and ends up feeling the full weight of his prison existence. His oldest child, Agatha, is gifted with an unimaginable strength and far-reaching fortitude that helps to keep the downtrodden Chisholm children united. Agatha even works across color lines, helping the Ruiz family, who are similarly affected by ghetto life. Then Devin Brooke comes along, a striking exciting young man who is duped by his friend to donate his sperm, which ultimately creates a link between Agatha and Devin that cannot be broken. Other players work behind the scenes and contribute to the redemptive arc within a story in which some are convicted of murder and others of carrying out major drug deals, homosexuality is forced upon unsuspecting prison neophytes, and men become transgendered against their will and are made to comply with multiple acts of depravity. All of these misfortunes and more are brought into play until all parties reach a well-rounded, happy-ever-after end.