On their quest for a safe place to call home, Chise and Teto cross paths with a dying woman and wind up entrusted with her infant daughter. And after uncovering a plot on the poor thing's life, they can't just leave her at an orphanage—so the girls decide to take baby Selene with them to the elusive Wasteland of Nothingness to keep her safe. Chise is resolved to raise Selene as her own, and thus begins an all-new journey for this little witch: motherhood!