Despite numerous hepatitis C virus infection studies, its pathogenesis and medical treatment have not been fully explained. This comprehensive volume, written by experts in the field, covers the most recent advances in the study of HCV, moving from basic research to clinical applications. The first chapters of this volume analyze the full spectrum of immune responses to HCV, taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions that explain the state of the art in IFN-alpha treatment of HCV patients and the effectiveness of therapy based on HCV genotypes. A major strength of the book is its clear and detailed examination of the immunobiology of HCV and the IFN-induced modification of the immune response. This book is an ideal volume for researchers, scientists, professionals, clinicians, physicians, and graduate students in infectious diseases, immunology, virology, microbiology, pharmacology, and medicine.