In one of Siberia's formerly closed cities, Alexandra Pavlova, an unemployed microbiologist, struggles to save her daughter's life. When she turns to Vladimir, her oldest friend, for help, she's drawn into Russia's underworld. His business dealings with the Iranians come to the attention of Sergei Borisov, an FSB (formerly the KGB) agent. Alexandra finds herself joining forces with Sergei to stop the export of a deadly virus in a race to save both her daughter and the world.