<p>The COVID-19 pandemic and overlapping global crises, including geopolitical conflict and climate change, have made achievement of the United Nations Sustainable Development Goals (SDGs) more challenging. The scientific community incre-singly recognizes the need to accelerate the adoption of evidence-based, scientifically-sound policies and actions to operationalize sustainable development.</p> <p>This report identifies key research priorities and possible actionable steps to operationalize sustainable development at the global and local levels. Although the scope of the challenges and opportunities are global with many research investigations and actions needed, Operationalizing Sustainable Development to Benefit People and the Planet presents research priorities and possible actionable steps for consideration by U.S. stakeholders</p> <p>.</p>