When Joe Patterson arrives in a rural upper Midwestern river town in order to fix up and sell his late father's "cabin," a host of issues for which he's not prepared confront him: the cabin is in shambles, his body aches, his checking account is almost empty, and he meets a twelve-year-old boy in need of help. A story of hope, loss, and redemption, Mississippi River Museum explores the unlikely friendship between two orphans who bond over fishing, bikes, and eating fried catfish.