When Artemisia Gentileschi arrives in Florence seeking a haven for her art, she faces instant opposition from the powerful Accademia, self-proclaimed guardians of the healing and necrotic magic that protect the city from plague and curses. As artists create their masterpieces, they add layer upon layer of magic drawn from their very life essence into the paint or marble, draining their power but producing works that will heal hundreds and inspire generations. The all-male Accademia jealously guards its power over art and architecture and has no place for an ambitious young woman arriving from Rome under a cloud of scandal. Alone and fighting for every commission, Artemisia begins winning allies among luminaries such Galileo and Michelangelo the Younger, as well as the wealthy and powerful Cristina de' Medici. But when the shadow of her infamous rape trial in Rome turns her thoughts to vengeance and an incendiary preacher turns his ire from Galileo to Florence's art world, Artemisia must choose between revenge and her dream of creating a legacy that will span the generations.