Professor Mitch Pine knows all too well the history of epidemics, so the startling new information he's discovered has him racing to the Centers for Disease Control in Atlanta. Mitch has uncovered a startling pattern: dramatic environmental changes always occurred prior to devastating outbreaks, and current climate change may be such a catalyst. But before his plane lands, Mitch's journey takes a terrifying turn. He is intercepted by a woman who represents a dangerous faction whose interest in Mitch's research opposes his mission to save lives. To secure Mitch's cooperation, his research assistant is being held hostage. With so many lives on the line, Mitch embarks on a turbulent trip around the world, uncovering pieces of the puzzle until he ultimately holds the key to prevent—or precipitate—global devastation. Unless he can find a way to stop the lunatics behind his abduction, a plague the likes of which the world has never known will be unleashed.