Giuseppina Pizzigoni (1870-1947) was a pioneer of the change in the vision of school education in Italy, and an autonomous interpreter of the impulse of transformation that lies at the origin of the progressive school, the active school, and the new school in Europe and the USA. In 1907, she conceived of the renewal of the Italian school, anticipating the structure of the comprehensive school and incorporating the nursery school with infants and children from 0 to 3 years of age. In 1911, she created the first Rinnovata Pizzigoni building, still standing today in Milan. The book explores the real evolution of the experimental method introduced in infant schools, and shows how the initial pedagogical idea can develop creatively, without being an imitation of a previous model.