This publication features a broad suite of statistical indicators characterizing the supply-and-use interactions of economic sectors within and across 25 economies of Asia and the Pacific. The indicators include sector- and economy-specific multipliers and linkages, trade orientation and openness, participation in global value chains, patterns of product specialization, and domestic agglomeration, among many others. Supplementing these analyses are special chapters on the economic impacts of the COVID-19 pandemic, the contribution of the digital economy, and the significance of activities related to real estate. All analyses and indicators draw on the Multiregional Input–Output database maintained by the Asian Development Bank.