Following a long-awaited wedding at Little Tombstone, both the bride and a guest fall ill after eating leftover tamales from the reception at the Bird Cage Cafe.

While Emma is still embroiled in trying to figure out why anyone in their right mind would try to poison the bride, more mayhem strikes the village of Amatista, and it's a race against time to catch a would-be killer before he (or she) succeeds in his (or her) evil schemes.