In the final days of Christmas 2019 I had an epiphany. I will never forget that night when I cried out as I saw a vision of that "little"! Since then, I have felt so dismal and would rather bury my head in the sand! No matter where I go and how fast I run, I can't forget that dream or catch that invisible "little" anymore! I found myself running away and I couldn't help it! I would ask myself, "To whom should I report to?", "What is the remedy other than running away?" These questions have brought me to author the fourth book on COVID-19. This series has covered the world's journey, experiences, and views since it all began. It was just a "little" and wasn't much. Before I knew it, it had infected the world entirely. It was supposed to pass by swiftly with "little" to be done. Then it proceeded to be remedied by a face mask for two weeks, followed by just one dose of a vaccine. All the while, the nightmare never ended. The "little" invader of human cells creeped in unnoticed; in the darkness, and left imprinted memories for generations to come. It has changed our day to day lives for more than two years, shaped our daily living, and will affect our future for decades to come. The "little" wasn't the least as the world thought, and was indeed ignored, as many downplayed its sharp spikes until it killed millions and infected hundreds of millions. The world is living in tears and terrors, broken hearted, and in fear. "What is next?'', I would ask myself, as it appears it is only getting worse as the news of wars and economic collapse are already at our door. To make things grave, many forever lost! But now, lessons must be learned and the wisdom of the past shall carry the world to the future. Over 16 sections and 188 chapters, the book represents the last of the author's series of COVID-19 as it covers the last year of the pandemic and the most recent events. It represents the author's views and highlights a wide variety of topics ranging from living stories, medical and political to philosophical views and experiences. The book reflects the author's Christian and medical devotions as it covers many true patients stories, patients' testimonials, medical events, and resident education.