Alan is a failing agent at a barely solvent talent agency. He's under investigation for sexual harassment, his flight attendant wife might be sleeping with a small-town crossing guard, and he's tens of thousands of dollars in debt––all from strippers and "tantric massages." Something's gotta give. Approaching 40 and inspired by a screaming self-help guru who instructs him to stop being such a pussy, Alan takes on the guru's motto––Give Zero Fucks––in hopes of turning his life around. He embarks on a misguided journey through faux spirituality, sexual obsession, jungle shamanism, life-coaching, and Jewish mishegas, trying to dig himself out of his self-inflicted mess.