Sarah Livingston is a recent graduate of the Medical School at the University of Nebraska. Her older sister, Rachel, who's been put on bedrest as a result of a difficult pregnancy, has asked Sarah to run her medical practice for her. Sarah decides to take the chance, even though it will put her relationship with Doctor Grant McCall on hold. While in Hoonah, Alaska, Sarah meets and locks horns with Jake Roundtree, a Physician's Assistant with his own ideas as to how the practice needs to be managed. Will these two find a common ground? Or will Sarah kick the dust of Hoonah off her feet and hightail it back to her boyfriend, and to her lucrative career?