The Chemistry of Hyperpolarized Magnetic Resonance Probes
ebook ∣ Advances in Magnetic Resonance Technology and Applications
By Eul Hyun Suh
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The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included.
- Helps readers understand the structural features that determine the properties of HP-probes, such as chemical shift and relaxation times
- Aids readers in selecting stable isotope labeled probes for hyperpolarized NMR/MRI applications
- Teachers readers how to use the most appropriate synthetic methodology for the labeled probes
- Covers how to find the most suitable polarization technique (DNP, PHIP etc.) for the probe