In 2018 and 2019, a teacher penned short books whose aim was to instruct neuroanatomy not in the manner of textbooks, but rather by exploring honest questions raised in the study of human brain structure. Why is there a crossed organization of pathways? Why has the frontal brain been implicated in language? How does one navigate the brainstem as if in a very familiar place? In this first of two volumes, Miyawaki addresses the three queries in a new edition of his prior work. The Autumn Brain Seminars is a summation of his decades of teaching in hospitals and classrooms.