Since the introduction of transarterial tumour therapy of the liver at the beginning of the 1970s, its indications have continuously increased. The constant further development of angiography techniques on the one hand and improved understanding of the pathogenesis of tumours on the other have today led to transvascular therapy, such as transarterial chemoembolisation (TACE), becoming one of the most important approaches in the management of liver tumours. After the indication for it has been made on an interdisciplinary basis, the different disciplines, essentially radiology, surgery and internal medicine, can together achieve an optimum treatment outcome for patients.