International Review of Cytology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles in this volume include the role and distribution of retinoic acid during CNS development, the role of receptor-associated protein (RAP) as a molecular chaperone for members of the LDL receptor family, the biology of cortical granules, acetylcholinesterase genes in the nematode caenorhabditis elegans, and reciprocal regulation of endothelin-1 and nitric oxide. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.*The Role and Distribution of Retinoic Acid during CNS Development*The Roles of Receptor-Associated Protein (RAP) as a Molecular Chaperone for Members of the LDL Receptor Family*The Biology of Cortical Granules*Acetylcholinesterase Genes in the Namatode Caenorhabditis elegans*Receprocal Regulation of Endothelin-1 and Nitric Oxide: Relevance in the Physiology and Pathology of the Cardiovascular System