A variety of complementary techniques and approaches have been used to characterize peptide and protein unfolding induced by temperature, pressure, and solvent. Volume 62, Unfolded Proteins, assembles these complementary views to develop a more complete picture of denatured peptides and proteins. The unifying observation common to all chapters is the detection of preferred backbone confirmations in experimentally accessible unfolded states. - Peptide and protein unfolding induced by temperature, pressure, and solvent - Denatured peptides and proteins - Detection of preferred backbone confirmations in experimentally accessible unfolded states