Praise for the Series:"The series which all immunologists need."—The Pharmaceutical Journal"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."—Science"Deserves a permanent place in biomedical libraries as an aid in research and in teaching."—Journal of Immunological MethodsKey Features:* The role of CD40 and its ligand, gp39, as central players in the regulation of B cell growth and differentiation* Prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors* Transcription factors of functionally mutant mice are highly relevant to understanding hemopoiesis and B cell genesis in vivoHIV infection of xenotransplanted mice compared with natural HIV and SIV infections* The expression and role of cytokines in Rheumatoid Arthritis and in seronegative arthritis* The functions of the surrogate light chain in B cell development* Mechanisms that regulate cytokine activity and the generation and function of sCR as cytokine anatogonists and/or cytokine "carriers" in vivo* Potential transducing molecules involved in signaling processes and which mark the difference between signaling through IL-2R and IL-4R