Economic corridor development (ECD) is pursued by developing member countries of the Asian Development Bank to spur economic growth. In Central Asia, ECD is being piloted as potential is immense but remains largely untapped. This publication provides a road map for developing the Shymkent–Tashkent–Khujand Economic Corridor (STKEC) connecting Kazakhstan, Tajikistan, and Uzbekistan. It proposes specific action plans for six intertwined thematic areas. An institutional framework to operationalize the STKEC development is also presented, along with possible investment projects in bordering cities and oblasts of the three countries.