Organ and tissue transplants can be the last resort for a range of life-saving and life-improving treatments. This opportunity usually only becomes available when someone donates their organs or tissues upon their death. Although the latest organ donation figures have reached a record high, the total however, only equates to a national organ donor rate of 13.8 per million, which suggests more can be done to help Australians who are on transplant waiting lists. This book addresses the misconceptions and facts about organ and tissue donation and registration with the aim of raising community awareness in an effort to boost donation rates. It also explores a range of ethical issues around consent and objection, such as ‘opt-out’ system proposals, religious considerations, the brain death debate, altruistic living tissue and organ donation, the illegal market in body parts, and animal to human transplantation (xenotransplantation). What does it take to give the gift of life? The topic is presented in two chapters: Organ and tissue donation in Australia; Ethics of organ donation.