After a crooked Senator sends the world into total chaos with an experimental chemical weapon, a teacher and his chemistry class begin looking for a cure. When the Senator discovers their efforts, he convinces the President and Congress to bomb the cities in an effort to stop them. What results is a post apocalyotic world where vampires, werewolves, and zombies-the results of four different chemical weapons-roam infecting others.

Hunters, Sowers, Reapers, and remnants of the world's militaries also roam the continents. Sowers and Reapers are the remnants of the religious community. Hunters hunt the undead. And all are on a collision course.