While walking home one night, homeless teen Crispin Lipton is bitten by an unusually large wolf, catapulting his life onto a new trajectory. While trying to cope with what has happened and the fear of dying, Crispin is taken to Bristol Manor, a Wolf House for other teenagers like him.

Life doesn't get any easier for Crispin when a friend is kidnapped by a group bent on exposing the existence of supernatural creatures. Choosing to join a quest to retrieve the young boy, Crispin accompanies his two new friends as they battle groups of rogue werewolves, an old high school bully, and werewolf hunters in hopes of completing their mission.

Their journey is anything but smooth and the shocking secrets Crispin uncovers about his family will change his life forever.