When the last outbreak of human vampirism occurred in the narrow oasis of New Mexico's lower Rio Grande Valley, the oral tradition that had been passed on for centuries had yet again been sadly reconfirmed. Every two decades or so, one or more bloodthirsty ghouls appears and preys upon the vulnerable members of this small but tightly knit community.

As a young curandera, or healer, Lorena Pastore was only twenty-five years old when the last outbreak occurred, and she remembers the shocking horror that spread throughout her beloved community at the time. She erroneously predicted that she would be well into her middle years of life for the next outbreak, but sadly, that is not the case.

After a foolish man commits an egregious violation during a spiritual cleansing ritual, the seven years of peace is shattered. The malignant disease of human vampirism is re-incarnated, and Lorena is forced to flee across the Mexican border with a five-year-old in peril. Nathan's father is becoming a lethal vampire, and the boy is now hunted-as is Lorena as she takes the child into her care and fights the outbreak destined to destroy her home and people.