Detective Frank Vandegraf isn't sure how serious to regard the claim of an eccentric university professor that his wife is trying to kill him, especially when a relative insists that she's gone into hiding because the husband has actually threatened to kill his wife. When the professor turns up murdered shortly thereafter, with a mysterious note lying on his chest that says 'IT'S HER FAULT', Frank redoubles his efforts to locate the missing wife, his prime suspect. But when he does, the case takes a really bizarre turn...