The development of organic intermediates requires high performance and original technologies. This book reviews recent work on some fifteen basic technologies in intermediates development including; hydrogenation, fluorination, chlorination, nitration, enzymatic catalysis, hydroxylation, alkylation, carboxylation and the Friedel Crafts reaction. Problems and industrial constraints involved in industrial development are highlighted from a research viewpoint and new technologies with potential for use in industry, particularly catalyst-based technologies clean chemical processes, are described. A chapter dealing with reviews on sodium amidure and polymerisation inhibitors is included.