Tough-as-nails Doreen Sizemore, decides she would rather fight a rabid skunk than set foot outside her tiny Kentucky town ever again. She's tired of stumbling upon murders in her travels, and doesn't intend to ever get involved in another one. But she can't turn down one more trip when she accidentally wins a vacation to Las Vegas from the local IGA. Unfortunately, her brother joins her there and gets himself into a mess at a casino. Trying to spirit him out of town without getting caught teaches Doreen the meaning of "What happens in Vegas stays in Vegas!"