Talia and Scarlett are the perfect opposite of each other, except that they are identical twins. Talia is focused, brainy, and finds interacting with people strenuous. Scarlett lives life with her arms wide open to each new experience and is the life of every party. They are the perfect foils for each other, weak where the other is strong and vice versa. Unfortunately, one of them is fighting a losing battle, and when she requests one final hurrah to finish her bucket list, her sister can't refuse her.

Dr. Zane Michaels has devoted his life to developing treatment protocols for those who have no further treatment options. Driven by and married to his career, he is okay bypassing personal human relationships. Until he is presented with the machinations of two resourceful women who change his world in ways he isn't prepared for, when he is asked to help make the trip home more comfortable for one of them, he faces the biggest challenge in his life. For once, the mission is not about finding a cure for cancer but about healing the hearts of those involved in the journey.