This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series. - Discusses methods currently used in preclinical and clinical gene therapy - Covers the use of adeno-associated virus delivery for treatment of Parkinson's disease