Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. - This volume includes reviews on some of the hottest topics in pharmacology, including: - Multidrug resistance and the MDR1 gene in gene therapy - Regulation of calcium channels in epithelial cells - Gene therapy and vascular disease - Potential therapeutic applications for Heparin - Calcium channel blockers - Antithrombotic agents - Regulation of potassium channels in epithelial cells