Anyone can do this practice. However, you are permitted to do the visualization of Vajrasattva together with his wisdom mother only if you have received a highest yoga tantra initiation. Otherwise, you should visualize the solitary form of Vajrasattva above your head.

By Lama Zopa Rinpoche

Students can use this practice text to purify negative karmas with the four opponent powers: the powers of regret, reliance, remedy, and restraint. The practice is performed in dependence on Vajrasattva, a buddha considered particularly powerful for the purification of negativities.

As it is taught that even small negative karmas can grow exponentially until they are purified, Lama Zopa Rinpoche encourages students to engage in purification practices daily.

2020 edition.