Recovering from her recent battles with Nazis and mobsters and still grieving the loss of her best friend, Valorie Van Helsing has a new threat looming—and this one wants her blood.

As Valorie tries to get back to her life and settle into a new school year, she finds that both the school and Tarrytown are crawling with vampires—vampires that not only want to destroy the Van Helsing family but also conspire to spread their evil in a mind control plot to terrorize the world.

To make matters worse, one of the vampires harbors a special hatred for Valorie—a hatred harking back to the Van Helsing family's archenemy—Dracula himself.