In the land of towering mountains and howling winds, the young man named Preacher has found a home. In the wilds, he has learned the rules of survival—and he has killed in order to live.

Now, something is forcing Preacher out of his Rocky Mountain range for the so-called "civilized" world. It is the memory of a woman, his first and only true love. It is her blood calling out for revenge.

The murder's deadly trail will lead Preacher from St. Louis eastward, with a stopover at his childhood home. But even the rekindled fire of family won't detain Preacher from his pursuit and soon he'll arrive at the site of his blood vengeance: Philadelphia Pennsylvania—the city of Brotherly Love.

But even the best laid plans of mice and mountain men often go awry...