The Seekers is the story of Jessie E. Sampter's exploration of philosophical questions about religion, the meaning of life, the nature of art, and much more with a group of high school students. The work shows their quest to find meaning in life when sectarian religions differed among themselves and were based partially on myth and superstition. Moreover, the book explored how spiritual life was possible in a period of science and evolutionary theory, and several other important questions.