Only recently has the role of trace elements been appreciated. Trace minerals do not exist by themselves but in relationship to one another. Too much of one trace mineral can lead to imbalances in others resulting in disease, rather than the absence of disease. Mineral deficiencies and imbalances are known to affect and be involved in disorders of the cardiovascular system, gastrointestinal, muscular, skeletal, neurological, immune and endocrine systems. However, it is obvious when studying the relationship of minerals to human health that keeping the level of minerals in balance in every tissue, fluid, cell, and organ in the human body may be a key to maintaining overall human health, which includes cancer and disease prevention.