The Squaw Man was adapted from a western/drama stage play written by Edwin Milton Royle. The story revolves around Capt. James Wynnegate takes the blame when his brother, Sir Henry, steals from a charitable fund to save his family from humiliation. So, he relocates to America, buys a ranch in Wyoming, and marries Nat-u-ritch, a Native American woman. But things take a turn after the birth of his son when James is surprised by the arrival of Lady Diana, his brother's wife.