Stem Cells: The Beginning of Regenerative Medicine deals with the significance of stem cells for the manufacture of regenerative medicines along with the techniques and approaches involved. It comprises future perspective of stem cells and tissue engineering together with the opportunities and challenges associated with it. It provides the reader with fundamental knowledge of stem cell technology in order to better understand its application in the production of regenerative medicines, the use of these regenerative medicines for kidney and to deal with the challenges associated with the application of stem cells. This book also discusses about engineered stem cell niche matrices for rotator cuff tendon regenerative engineering, application of nanomaterials in stem cell regenerative medicine of orthopedic surgery, regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy and cryopreserved dental pulp tissues of exfoliated deciduous teeth is a feasible stem cell resource for regenerative medicine.