With this special issue of the International Journal of Mentoring and Coaching in Education (IJMCE) we aimed to examine potential benefits, challenges, and implications of mentorship and coaching as supportive structures for the well-being of educational professionals and students in a variety of educational contexts, including compulsory and post-compulsory educational settings. We also intended to contribute to and enhance the body of literature pertaining to the role of mentoring and coaching in supporting the holistic well-being and ongoing learning and development of educators and students.