Missing Persons is a memoir about dealing with death in a culture that gives no help. As the last of her family, Greene's losses are stark, first her aunt, then her mother, in quick succession. She is as ill-equipped for the challenges of caring for a dying person at home as she is for the other losses, long repressed, that rise to confront her at this time: the suicide of her younger brother, the death of her father. As the professional identity on which she's based her selfhood comes to feel brittle and trivial, she is catapulted into questions of "who am I?" and "what have I done with my life?"

The memoir is structured as an account of her mother's and aunt's final days and the year that follows, a year in which she reconstructs her life. This is a powerful story about family, what it means to have one, to lose one, never to have made one, and what, if anything, might take its place. It's the story of a vexed mother-daughter relationship that mellows with age. It is also a search for home, as the very landscape shifts around her and the vast orchards are dug up and paved over for tract housing, strip malls, freeways, and the Santa Clara Valley, once known as the Valley of Heart's Delight, is transformed to "Silicon."