The Pharmacology, being a subject involving drugs needs precision, perfection and application. Therefore meticulous planning is required. This book emphasizes on various facets- the experimenter should know before actual start of experiment. It introduces to regulatory aspects– CPCSEA, IAEC and part B to be submitted. The knowledge of basic pharmacological concepts, making PSS, drug solution making and dilutions are important for beginners. The world and CPCSEA are stressing for Humane Approach in use of experimental animals and worthwhile to go through the same. Computer Assisted Learning (CAL) or simulation is one of the best ways to explain experiments in reinforcing manner in addition to following humane approach. Experimentation demands several skills before actual experiments and description + pictures can help in learning necessary techniques. Same is the importance of instruments and knowledge of instruments and their operations prior to study always pay off. The knowledge about bioassay is must. The new approach is applied for explaining biostatistics i.e. performing calculations using softwares. Most of the text information is supported with pictures / diagrams to make it easy for understanding. Once the basic is learned well the experimenter can move to actual experiments and accordingly forthcoming volumes will be devoted to in vivo and in vitro experiments.