Folklore, medicine, and superstition in the Georgia mountains. Dr. Waycross knows bleeding and blistering, the best scientific medicine of 1822. He arrives in the Georgia mountains to bring his modern methods to the superstitious masses. The local healers, the Winter sisters, claim to treat yellow fever, consumption, and the hell-roarin' trots just as well as he can. Some folks call the sisters herb women; some call them witches. Waycross calls them quacks. But when the threat of rabies-incurable and fatal-comes to town, Dr. Waycross and the Winter sisters must combine their science and superstition in a desperate search for a remedy. Can they find a miracle cure, or has the age of miracles passed?